Read the synopsis on Goodreads.
The first thing I’m going to say is that Skios would make a pretty funny movie because anything with mistaken identity is funny.
Dr. Norman Wilfred is going to Skios, a private island on Greece, to give a lecture. On the same flight goes Oliver Fox, kind of a free spirit-modern-hippie who is there for a rendezvous with a married woman. Nikki, in charge of picking the Dr. at the airport picks Oliver instead and that is when the confusion starts.
The book is funny but not hilarious. I liked the humor and the confusion but at some point became tired of it. Why? God only knows!
Also, the humor is more for an adult audience than YA; they might not see the hilarity in mistaking a Dr. by a common lover.
Not so favorable reviews here and here.